- The control of impurities in amitriptyline hydrochloride using a reversed-phase hybrid stationary phase.
The control of impurities in amitriptyline hydrochloride using a reversed-phase hybrid stationary phase.
Pharmeuropa scientific notes (2007-08-11)
S P Dixon, A Lodi, J H M Miller, G G Skellern
PMID17687889
초록
An isocratic reversed-phase liquid chromatographic method is described using a hybrid column for the control of synthetic impurities potentially found in amitriptyline hydrochloride. The method has been validated and is capable of controlling impurities to 0.1 per cent.
MATERIALS