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Merck
  • Immobilised vitamin B12 as a biomimetic model for base-off/histidine-on coordination.

Immobilised vitamin B12 as a biomimetic model for base-off/histidine-on coordination.

Chemical communications (Cambridge, England) (2011-09-20)
Christine Männel-Croisé, Felix Zelder
초록

Immobilisation of vitamin B12 allows synthesising a biomimetic base-off/histidine-on complex that resembles structural features of cobalamin dependent enzyme active sites.

MATERIALS
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Sigma-Aldrich
5,6-Dimethylbenzimidazole, ≥99%