- Inhalable Ipratropium Bromide Particle Engineering with Multicriteria Optimization.
Inhalable Ipratropium Bromide Particle Engineering with Multicriteria Optimization.
AAPS PharmSciTech (2016-11-23)
Bhavani Prasad Vinjamuri, Rahul V Haware, William C Stagner
PMID27873181
초록
Spray-dried ipratropium bromide (IPB) microspheres for oral inhalation were engineered using Quality by Design. The interrogation of material properties, process parameters, and critical product quality attributes interplay enabled rational product design. A 2
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