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Process Intensification of Monoclonal Antibody Purification Process



WEBINAR

Process intensification of mAb purification offers a viable approach to boost productivity with minimal facility modification. This approach can also impart flexibility for handling multiple clinical and commercial programs with varying upstream titers.

We will provide an overview of an intensified monoclonal antibody purification process, leveraging best-in-class purification technologies offered by us. We will present harvest preconcentration enabled intensified capture, intensified polishing via flowthrough polishing technologies, and intensified drug delivery by leveraging viscosity reduction platform, cassette feed channel designs, and Single Pass Tangential Flow Filtration (SPTFF).

In this webinar, you will learn:

  • How to intensify capture by harvest preconcentration
  • How to intensify polishing by leveraging flowthrough polishing technologies
  • How to leverage viscosity-reducing excipients, screens, and SPTFF for high-concentration formulation

Speaker

Akshat Gupta, Ph.D.

Akshat Gupta, Ph.D.

MilliporeSigma

Associate Director, Global BioPharma Center of Excellence

Akshat Gupta is the associate director of applications engineering, Global Biopharma Center of Excellence. Akshat has more than 10 years of experience in the biopharmaceutical industry, focused on process development and manufacturing sciences. His areas of specialization include cell culture clarification and tangential flow filtration. He holds an M.S. and a Ph.D. in chemical engineering from the University of Massachusetts, Lowell, where is also an adjunct faculty member in the chemical engineering department.

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