MilliporeSigma

PIN1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1

Synonyms:
DOD, UBL5
Species:
UniProtKB ID:
Gene ID:
  • Human(5300) Summary: Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
  • Mouse(23988) protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
  • Rat(298696) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • Thale Cress(843693) auxin efflux carrier component 1
  • Zebrafish(393721) protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
  • chicken(100859153) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • dog(484963) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • domestic cat(101087904) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • cow(535470) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • sheep(101110756) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • domestic guinea pig(100726337) peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • naked mole-rat(101708402) peptidylprolyl cis/trans isomerase, NIMA-interacting 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-Pin1 (pSer16) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-PIN1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
Anti-phospho-Pin1 (pSer16) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Anti-PIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-PIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

Small Molecule - Inhibitor

Product Number
Description
Species
Cycloheximide, ≥90% (HPLC),
Species
human
Cycloheximide solution, Ready-Made Solution, microbial, 100 mg/mL in DMSO, Suitable for cell culture,
Species
human
Cycloheximide, from microbial, ≥94% (TLC),
Species
human
Cycloheximide, Biotechnology Performance Certified,
Species
human
Cycloheximide solution, 0.1%, suitable for microbiology,
Species
human

Proteins

Product Number
Description
Species
PrEST Antigen PIN1, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
PrEST Antigen PIN1, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PIN1,
Species
human
MISSION® esiRNA, targeting mouse Pin1,
Species
mouse