MilliporeSigma

AKR1B1

aldo-keto reductase family 1, member B1 (aldose reductase)

Synonyms:
ADR, ALDR1, ALR2, AR
Species:
UniProtKB ID:
Gene ID:
  • Human(231) Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
  • Rat(24192) aldo-keto reductase family 1, member B1 (aldose reductase)
  • Domestic Rabbit(100009122) aldo-keto reductase family 1, member B1 (aldose reductase)
  • naked mole-rat(101720124) aldo-keto reductase family 1, member B1 (aldose reductase)
  • domestic guinea pig(100718017) aldo-keto reductase family 1, member B1 (aldose reductase)
  • Zebrafish(415138) aldo-keto reductase family 1, member B1 (aldose reductase)
  • domestic cat(101095406) aldo-keto reductase family 1, member B1 (aldose reductase)
  • cow(317748) aldo-keto reductase family 1, member B1 (aldose reductase)
  • dog(607537) aldo-keto reductase family 1, member B1 (aldose reductase)
  • sheep(101120824) aldo-keto reductase family 1, member B1 (aldose reductase)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-AKR1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-AKR1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-AKR1B1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-AKR1B1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-AKR1B1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, human, mouse, pig, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, 97%,
Species
rat
Fluorene-9-carboxylic acid, 96%,
Species
rat
Hippuric acid, 98%,
Species
rat
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Species
human

Proteins

Product Number
Description
Species
Aldose Reductase human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human AKR1B1,
Species
human