ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
Synonyms:
ATP6F, HATPL, VMA16
Species:
Human ATP6V0B (533), Mouse Atp6v0b (114143), Rat Atp6v0b (298451), chicken ATP6V0B (424575), Zebrafish atp6v0b (321724), dog ATP6V0B (482528), cow ATP6V0B (505684), domestic cat ATP6V0B (101084376), sheep ATP6V0B (101114221), naked mole-rat Atp6v0b (101718458)
UniProtKB ID:
Gene ID:
- Human(533) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the transmembrane V0 domain and is the human counterpart of yeast VMA16. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(114143) ATPase, H+ transporting, lysosomal V0 subunit B
- Rat(298451) ATPase, H+ transporting, lysosomal V0 subunit B
- chicken(424575) ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
- Zebrafish(321724) ATPase, H+ transporting, V0 subunit B
- dog(482528) ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
- cow(505684) ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
- domestic cat(101084376) ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
- sheep(101114221) ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
- naked mole-rat(101718458) ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
- domestic guinea pig(100720289) ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ATP6V0B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot