MilliporeSigma

CD8A

CD8a molecule

Synonyms:
CD8, Leu2, MAL, p32
Species:
UniProtKB ID:
Gene ID:
  • Human(925) Summary: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(12525) CD8 antigen, alpha chain
  • Rat(24930) CD8a molecule
  • domestic guinea pig(100379570) CD8 antigen, alpha chain
  • naked mole-rat(101720748) CD8a molecule
  • Zebrafish(677754) CD8 antigen, alpha polypeptide
  • chicken(403158) CD8a molecule
  • dog(403157) CD8a molecule
  • domestic cat(493799) CD8a molecule
  • cow(281060) CD8a molecule
  • sheep(101103464) CD8a molecule
  • chicken(428800) CD8a molecule

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CD8A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CD8a (Mouse), clone 53-6.7, biotin conjugate Antibody, clone 53-6.7, from rat, purified by affinity chromatography,
Species Reactivity
mouse
Application
flow cytometry
Anti-CD8a (Mouse), PE-Cy7, clone 53-6.7 Antibody, clone 53-6.7, from rat, PE-Cy7,
Species Reactivity
mouse
Application
flow cytometry
Anti-CD8a (human), FITC, clone RPA-T8 Antibody, clone RPA-T8, from mouse, FITC conjugate,
Species Reactivity
human
Application
flow cytometry
Anti-CD8A antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot

Proteins

Product Number
Description
Species
Monoclonal Anti-CD8A antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL1529, purified immunoglobulin, buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CD8A,
Species
human