MilliporeSigma

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

Synonyms:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Species:
UniProtKB ID:
Gene ID:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

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ELISA

Product Number
Description
Species
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Cadherin-pan antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-E-Cadherin Antibody, clone 2Q9Y7, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-CD324-PE antibody produced in mouse, clone 67A4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-E-Cadherin Antibody, clone 67A4, clone 67A4, Chemicon®, from mouse,
Species Reactivity
human
Application
flow cytometry
western blot
Anti-E-Cadherin/CD324 Antibody, clone 19A11, ,
Species Reactivity
canine, human
Application
ELISA
immunocytochemistry

inhibition assay

western blot

Cell Lines

Product Number
Description
Species
MCF10A CELLS CDH1 (-/-), ,
Species
human

Proteins

Product Number
Description
Species
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Species
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CDH1,
Species
human
MISSION® esiRNA, targeting mouse Cdh1,
Species
mouse