MilliporeSigma

CDH4

cadherin 4, type 1, R-cadherin (retinal)

Synonyms:
CAD4, RCAD
Species:
UniProtKB ID:
Gene ID:
  • Human(1002) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(12561) cadherin 4
  • Rat(114588) cadherin 4
  • naked mole-rat(101726465) cadherin 4, type 1, R-cadherin (retinal)
  • domestic guinea pig(100720758) cadherin 4, type 1, R-cadherin (retinal)
  • sheep(101122716) cadherin 4, type 1, R-cadherin (retinal)
  • chicken(419222) cadherin 4, type 1, R-cadherin (retinal)
  • cow(525796) cadherin 4, type 1, R-cadherin (retinal)
  • dog(100685099) cadherin 4, type 1, R-cadherin (retinal)
  • Zebrafish(30297) cadherin 4, retinal
  • domestic cat(101085708) cadherin 4, type 1, R-cadherin (retinal)

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ELISA

Product Number
Description
Species
Human Cadherin-4 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CDH4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-CDH4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, mouse, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CDH4,
Species
human
MISSION® esiRNA, targeting mouse Cdh4,
Species
mouse