MilliporeSigma

CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

Synonyms:
ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
Species:
UniProtKB ID:
Gene ID:
  • Human(1134) Summary: The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2012]
  • Mouse(11435) cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
  • Rat(79557) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • dog(403757) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • domestic guinea pig(100729588) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • cow(338070) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • chicken(395608) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • sheep(101110120) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • Zebrafish(30725) cholinergic receptor, nicotinic, alpha polypeptide 1
  • naked mole-rat(101715747) cholinergic receptor, nicotinic, alpha 1 (muscle)

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Small Molecule - Agonist

Product Number
Description
Species
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Species
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat
Decamethonium bromide, crystalline,
Species
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Species
human, rat

Small Molecule - Antagonist

Product Number
Description
Species
1-Octanol, ACS reagent, ≥99%,
Species
mouse
1-Octanol, ≥98%, FCC, FG,
Species
mouse
1-Octanol, ReagentPlus®, 99%,
Species
mouse
1-Octanol, natural, ≥98%, FCC,
Species
mouse
1-Octanol, anhydrous, ≥99%,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CHRNA1 antibody produced in mouse, clone 2G5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-Nicotinic Acetylchone Receptor alpha 1 Antibody, clone 7C8.2, clone 7C8.2, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-CHRNA1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-CHRNA1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α1, α3, α5 Subunits) antibody produced in rat, clone mAb 35, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
chicken, eel, human
Application
immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
Hexamethonium chloride, solid (hygroscopic),
Species
human
Tetraethylammonium chloride, ≥98% (titration),
Species
human
Hexamethonium bromide, ,
Species
human
Kynurenic acid, ≥98%,
Species
rat, human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Species
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHRNA1,
Species
human