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MilliporeSigma

CYSLTR1

cysteinyl leukotriene receptor 1

Synonyms:
CYSLT1, CYSLT1R, CYSLTR, HMTMF81
Species:
UniProtKB ID:
Gene ID:
  • Human(10800) Summary: The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung. [provided by RefSeq, Jul 2008]
  • Mouse(58861) cysteinyl leukotriene receptor 1
  • Rat(114099) cysteinyl leukotriene receptor 1
  • domestic cat(101087714) cysteinyl leukotriene receptor 1
  • chicken(428691) cysteinyl leukotriene receptor 1
  • Zebrafish(553675) cysteinyl leukotriene receptor 1
  • domestic guinea pig(100135514) cysteinyl leukotriene receptor 1
  • naked mole-rat(101713226) cysteinyl leukotriene receptor 1
  • cow(782045) cysteinyl leukotriene receptor 1
  • dog(100686426) cysteinyl leukotriene receptor 1
  • dog(608345) cysteinyl leukotriene receptor 1

Custom & Knockdown Gene Products

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Small Molecule - Antagonist

Product Number
Description
Species
Zafirlukast, ≥98% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CLTR1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-CYSLTR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CYSLTR1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

Small Molecule - Ligand

Product Number
Description
Species
Cinalukast, ~98% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CYSLTR1,
Species
human
MISSION® esiRNA, targeting mouse Cysltr1,
Species
mouse