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DBI

diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)

Synonyms:
ACBD1, ACBP, CCK-RP, EP
Species:
UniProtKB ID:
Gene ID:
  • Human(1622) Summary: This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(13167) diazepam binding inhibitor
  • Rat(25045) diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
  • fruit fly(38784) Diazepam-binding inhibitor
  • dog(476115) diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
  • chicken(395263) diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
  • Zebrafish(393831) diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
  • sheep(101111606) diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
  • cow(768330) diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
  • Horse(100049822) diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
  • domestic cat(101082679) diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
  • naked mole-rat(101705205) diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
  • domestic guinea pig(100713514) diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DBI antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Dbi,
Species
mouse
MISSION® esiRNA, targeting human DBI,
Species
human