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DUSP9

dual specificity phosphatase 9

Synonyms:
MKP-4, MKP4
Species:
UniProtKB ID:
Gene ID:
  • Human(1852) Summary: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq, Jul 2008]
  • Mouse(75590) dual specificity phosphatase 9
  • Rat(293847) dual specificity phosphatase 9
  • sheep(101123448) dual specificity phosphatase 9
  • cow(614306) dual specificity phosphatase 9
  • dog(492240) dual specificity phosphatase 9
  • domestic guinea pig(100713707) dual specificity phosphatase 9
  • naked mole-rat(101717115) dual specificity phosphatase 9
  • domestic cat(101080951) dual specificity phosphatase 9

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-DUSP9 antibody produced in mouse, clone 2E3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay

western blot
Anti-DUSP9 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-DUSP9 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-DUSP9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human DUSP9,
Species
human
MISSION® esiRNA, targeting mouse Dusp9,
Species
mouse