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FBXO18

F-box protein, helicase, 18

Synonyms:
FBH1, Fbx18
Species:
UniProtKB ID:
Gene ID:
  • Human(84893) Summary: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(50755) F-box protein 18
  • Rat(291293) F-box protein, helicase, 18
  • domestic cat(101099563) F-box protein, helicase, 18
  • sheep(101112918) F-box protein, helicase, 18
  • naked mole-rat(101719984) F-box protein, helicase, 18
  • Horse(100070322) F-box protein, helicase, 18
  • chicken(416687) F-box protein, helicase, 18
  • Zebrafish(567995) F-box protein, helicase, 18
  • dog(487142) F-box protein, helicase, 18
  • cow(534383) F-box protein, helicase, 18
  • domestic guinea pig(100715614) F-box protein, helicase, 18

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FBXO18 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Fbxo18,
Species
mouse
MISSION® esiRNA, targeting human FBXO18,
Species
human