MilliporeSigma

GABRA2

gamma-aminobutyric acid (GABA) A receptor, alpha 2

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2555) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14395) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
  • Rat(289606) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • cow(282236) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • chicken(770511) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • naked mole-rat(101720776) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic guinea pig(100720796) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic cat(100286789) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Domestic Rabbit(100339376) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • sheep(101121265) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Horse(100061914) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • dog(482131) gamma-aminobutyric acid (GABA) A receptor, alpha 2

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Small Molecule - Agonist

Product Number
Description
Species
(±)-Baclofen, ≥98% (TLC), solid,
Species
human, rat
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Species
human
Piperidine-4-sulfonic acid, ,
Species
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
Isoguvacine hydrochloride, solid,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
5β-Pregnan-3α-ol-20-one, ,
Species
Bromazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Bromazepam, European Pharmacopoeia (EP) Reference Standard,
Species
human
Bromazepam, United States Pharmacopeia (USP) Reference Standard,
Species
human
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
β-Naphthoflavone, ≥98%,
Species
Muscimol, powder,
Species
2-Pyrrolidinone, purum, ≥98.0% (GC),
Species
2-Pyrrolidinone, ≥99%,
Species
2-Pyrrolidinone, 99%,
Species

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GABA A Receptor-Allophycocyanin antibody produced in mouse, clone S399-19,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor antibody produced in mouse, clone S399-19,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Atto 488 antibody produced in mouse, clone S399-19,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-FITC antibody produced in mouse, clone S399-19,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Horseradish Peroxidase antibody produced in mouse, clone S399-19,
Species Reactivity
human, rat
Application
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Harmane, 98%,
Species
human
Norharmane, crystalline,
Species
human
Flavone, ≥99.0%,
Species
human, rat, mouse
Chrysin, 97%,
Species
human, mouse
NO-711 hydrochloride, ≥98% (HPLC),
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Etomidate, >98% (HPLC), powder,
Species
human
Flumazenil, >99% (HPLC), solid,
Species
rat, human
Carbamazepine, powder,
Species
rat, human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
Etiocholan-3α-ol-17-one, ,
Species
human, rat
Ganaxolone, solid, ≥98% (HPLC),
Species
human, mouse
5α-Pregnan-3α-ol-20-one, solid,
Species
human, mouse, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Gabra2,
Species
mouse
MISSION® esiRNA, targeting human GABRA2,
Species
human