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GLUD1

glutamate dehydrogenase 1

Synonyms:
GDH, GDH1, GLUD
Species:
UniProtKB ID:
Gene ID:
  • Human(2746) Summary: This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.[provided by RefSeq, Sep 2009]
  • Mouse(14661) glutamate dehydrogenase 1
  • Rat(24399) glutamate dehydrogenase 1
  • naked mole-rat(101699446) glutamate dehydrogenase 1
  • domestic guinea pig(100722523) glutamate dehydrogenase 1
  • sheep(443239) glutamate dehydrogenase 1
  • cow(281785) glutamate dehydrogenase 1
  • dog(100684847) glutamate dehydrogenase 1
  • chicken(423612) glutamate dehydrogenase 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Glud1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
baboon, bat, bovine, human, monkey, mouse
Application
immunohistochemistry
western blot
Anti-GLUD1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-GLUD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-GLUD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-GLUD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Proteins

Product Number
Description
Species
L-Glutamic Dehydrogenase from bovine liver, Type III, lyophilized powder, ≥20 units/mg protein,
Species
cow
L-Glutamic Dehydrogenase from bovine liver, Type II, 50% glycerol solution, ≥35 units/mg protein,
Species
cow
L-Glutamic Dehydrogenase from bovine liver, Type I, ammonium sulfate suspension, ≥40 units/mg protein,
Species
cow
Glutamate Dehydrogenase (GlDH), from beef liver,
Species
cow

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Glud1,
Species
mouse
MISSION® esiRNA, targeting human GLUD1,
Species
human