MilliporeSigma

GRIK2

glutamate receptor, ionotropic, kainate 2

Synonyms:
EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
Species:
UniProtKB ID:
Gene ID:
  • Human(2898) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008]
  • Mouse(14806) glutamate receptor, ionotropic, kainate 2 (beta 2)
  • Rat(54257) glutamate receptor, ionotropic, kainate 2
  • chicken(428628) glutamate receptor, ionotropic, kainate 2
  • dog(481938) glutamate receptor, ionotropic, kainate 2
  • Thale Cress(836176) geminivirus rep interacting kinase 2
  • Zebrafish(556013) glutamate receptor, ionotropic, kainate 2
  • cow(615226) glutamate receptor, ionotropic, kainate 2
  • naked mole-rat(101697577) glutamate receptor, ionotropic, kainate 2
  • domestic guinea pig(100733104) glutamate receptor, ionotropic, kainate 2
  • sheep(101122701) glutamate receptor, ionotropic, kainate 2

Custom & Knockdown Gene Products

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Small Molecule - Agonist

Product Number
Description
Species
L-Glutamic acid hydrochloride, ≥99% (HPLC),
Species
human
(±)-AMPA, solid,
Species
rat
(S)-AMPA, ≥98%,
Species
mouse, human, rat
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat
(Aminomethyl)phosphonic acid, 99%,
Species
rat, human

Small Molecule - Antagonist

Product Number
Description
Species
CNQX, ≥98% (HPLC), solid,
Species
rat
NBQX disodium salt hydrate, ≥98% (HPLC),
Species
human
DNQX, ≥98% (TLC),
Species
mouse, rat, human
(±)-AMPA, solid,
Species
rat
(S)-AMPA, ≥98%,
Species
mouse, human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-GRIK2 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-GRIK2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-GRIK2 Antibody, clone 4B4L9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
(±)-AMPA, solid,
Species
rat
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GRIK2 (1),
Species
human
MISSION® esiRNA, targeting human GRIK2 (2),
Species
human