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IL1R2

interleukin 1 receptor, type II

Synonyms:
CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB
Species:
UniProtKB ID:
Gene ID:
  • Human(7850) Summary: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]
  • Mouse(16178) interleukin 1 receptor, type II
  • Rat(117022) interleukin 1 receptor, type II
  • domestic guinea pig(100723930) interleukin 1 receptor, type II
  • naked mole-rat(101710536) interleukin 1 receptor, type II
  • chicken(418715) interleukin 1 receptor, type II
  • dog(481330) interleukin 1 receptor, type II
  • cow(515700) interleukin 1 receptor, type II
  • domestic cat(101080961) interleukin 1 receptor, type II
  • sheep(101103308) interleukin 1 receptor, type II

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ELISA

Product Number
Description
Species
Human IL-1 sRII ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL1R2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Species Reactivity
human
Application
immunohistochemistry
Anti-IL1R2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-IL1R2 antibody produced in mouse, clone 1G12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay

western blot
Anti-IL1R2 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Il1r2,
Species
mouse
MISSION® esiRNA, targeting human IL1R2,
Species
human