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IL2RB

interleukin 2 receptor, beta

Synonyms:
CD122, IL15RB, P70-75
Species:
UniProtKB ID:
Gene ID:
  • Human(3560) Summary: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]
  • Mouse(16185) interleukin 2 receptor, beta chain
  • Rat(25746) interleukin 2 receptor, beta
  • sheep(101107088) interleukin 2 receptor, beta
  • dog(403439) interleukin 2 receptor, beta
  • domestic cat(101092622) interleukin 2 receptor, beta
  • naked mole-rat(101726369) interleukin 2 receptor, beta
  • Zebrafish(793920) interleukin 2 receptor, beta
  • domestic guinea pig(100730639) interleukin 2 receptor, beta

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL2RB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
western blot
Monoclonal Anti-CD122 antibody produced in mouse, clone TU27,
Species Reactivity
human
Application
flow cytometry
Anti-IL2RB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-phospho-IL-2Rβ/CD122 (pTyr364) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Monoclonal Anti-CD122-APC antibody produced in mouse, clone TU27,
Species Reactivity
Application
flow cytometry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Il2rb,
Species
mouse
MISSION® esiRNA, targeting human IL2RB,
Species
human