MilliporeSigma

ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

Synonyms:
CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Species:
UniProtKB ID:
Gene ID:
  • Human(3684) Summary: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(16409) integrin alpha M
  • Rat(25021) integrin, alpha M
  • Horse(100064803) integrin, alpha M (complement component 3 receptor 3 subunit)
  • dog(489928) integrin, alpha M (complement component 3 receptor 3 subunit)
  • sheep(443217) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic guinea pig(100135561) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic cat(101087957) integrin, alpha M (complement component 3 receptor 3 subunit)
  • cow(407124) integrin, alpha M (complement component 3 receptor 3 subunit)
  • naked mole-rat(101719288) integrin, alpha M (complement component 3 receptor 3 subunit)
  • Domestic Rabbit(100351865) integrin, alpha M (complement component 3 receptor 3 subunit)

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ELISA

Product Number
Description
Species
Human Integrin alpha-M ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD11b, low endotoxin antibody produced in rat, clone M1/70, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, nonhuman primates
Application
flow cytometry
Anti-ITGAM antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry
Anti-CD11b Antibody (human/mouse), Biotin, clone M1/70, clone M1/70, 0.5 mg/mL, from rat,
Species Reactivity
human, mouse
Application
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
Monoclonal Anti-CD11b-APC antibody produced in mouse, clone MEM-174,
Species Reactivity
Application
flow cytometry
Monoclonal Anti-CD11b antibody produced in rat, clone M1/70,
Species Reactivity
human, mouse, nonhuman primates, rabbit
Application
flow cytometry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Itgam,
Species
mouse
MISSION® esiRNA, targeting human ITGAM,
Species
human