ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
Synonyms:
CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7
Species:
Human ITGB2 (3689), Mouse Itgb2 (16414), Rat Itgb2 (309684), Horse ITGB2 (100056128), naked mole-rat Itgb2 (101703921), domestic guinea pig Itgb2 (100727919), domestic cat ITGB2 (101087258), dog ITGB2 (403770), chicken ITGB2 (396181), Zebrafish itgb2 (557797) ...More
UniProtKB ID:
Gene ID:
- Human(3689) Summary: The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(16414) integrin beta 2
- Rat(309684) integrin, beta 2
- Horse(100056128) integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- naked mole-rat(101703921) integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- domestic guinea pig(100727919) integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- domestic cat(101087258) integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- dog(403770) integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- chicken(396181) integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- Zebrafish(557797) integrin, beta 2
- cow(281877) integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- sheep(494433) integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD18 antibody produced in rat, clone M18/2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
mouse
Application
flow cytometry
Monoclonal Anti-CD18, low endotoxin antibody produced in rat, clone M18/2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
mouse
Application
flow cytometry
Monoclonal Anti-CD18 antibody produced in mouse, clone IVA35, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
bovine
Application
flow cytometry
Anti-Integrin β2 [CD18] Antibody, clone MEM 48, Chemicon®, from mouse,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Integrin β2 Antibody, clone P4H9, azide free, clone P4H9, Chemicon®, from mouse,
Species Reactivity
human
Application
immunohistochemistry