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ITGB4

integrin, beta 4

Synonyms:
CD104
Species:
UniProtKB ID:
Gene ID:
  • Human(3691) Summary: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(192897) integrin beta 4
  • Rat(25724) integrin, beta 4
  • domestic guinea pig(100718717) integrin, beta 4
  • naked mole-rat(101697313) integrin, beta 4
  • domestic cat(101080415) integrin, beta 4
  • Horse(100051679) integrin, beta 4
  • sheep(101119919) integrin, beta 4
  • cow(506995) integrin, beta 4
  • Zebrafish(335269) integrin, beta 4
  • chicken(417374) integrin, beta 4
  • dog(483318) integrin, beta 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-ITGB4 (pTyr1510) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Integrin β4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-ITGB4 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL6973, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-ITGB4 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL6972, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Integrin beta 4 (ITGB4/CD104) Antibody, clone 5Z9P3, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Itgb4,
Species
mouse
MISSION® esiRNA, targeting human ITGB4,
Species
human