MAP3K11
mitogen-activated protein kinase kinase kinase 11
Synonyms:
MEKK11, MLK-3, MLK3, PTK1, SPRK
Species:
Human MAP3K11 (4296), Mouse Map3k11 (26403), Rat Map3k11 (309168), domestic guinea pig Map3k11 (100730722), domestic cat MAP3K11 (101098654), naked mole-rat Map3k11 (101718575), sheep MAP3K11 (101108969), Domestic Rabbit MAP3K11 (100356691), cow MAP3K11 (514210), dog MAP3K11 (483732)
UniProtKB ID:
Gene ID:
- Human(4296) Summary: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008]
- Mouse(26403) mitogen-activated protein kinase kinase kinase 11
- Rat(309168) mitogen-activated protein kinase kinase kinase 11
- domestic guinea pig(100730722) mitogen-activated protein kinase kinase kinase 11
- domestic cat(101098654) mitogen-activated protein kinase kinase kinase 11
- naked mole-rat(101718575) mitogen-activated protein kinase kinase kinase 11
- sheep(101108969) mitogen-activated protein kinase kinase kinase 11
- Domestic Rabbit(100356691) mitogen-activated protein kinase kinase kinase 11
- cow(514210) mitogen-activated protein kinase kinase kinase 11
- dog(483732) mitogen-activated protein kinase kinase kinase 11
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MLK3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Monoclonal Anti-MAP3K11, (C-terminal) antibody produced in mouse, clone 3D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
proximity ligation assay
western blot
immunohistochemistry
proximity ligation assay
western blot
Proteins
Product Number
Description
Species
MLK3 (1-488), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species