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MAP3K2

mitogen-activated protein kinase kinase kinase 2

Synonyms:
MEKK2, MEKK2B
Species:
UniProtKB ID:
Gene ID:
  • Human(10746) Summary: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008]
  • Mouse(26405) mitogen-activated protein kinase kinase kinase 2
  • Rat(171492) mitogen activated protein kinase kinase kinase 2
  • cow(504592) mitogen-activated protein kinase kinase kinase 2
  • Horse(100050628) mitogen-activated protein kinase kinase kinase 2
  • naked mole-rat(101726195) mitogen-activated protein kinase kinase kinase 2
  • domestic guinea pig(100723690) mitogen-activated protein kinase kinase kinase 2
  • sheep(101109858) mitogen-activated protein kinase kinase kinase 2
  • domestic cat(101096406) mitogen-activated protein kinase kinase kinase 2
  • dog(612902) mitogen-activated protein kinase kinase kinase 2
  • chicken(424225) mitogen-activated protein kinase kinase kinase 2
  • Zebrafish(558321) mitogen-activated protein kinase kinase kinase 2

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MAP3K2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, pig
Application
western blot
Anti-MAP3K2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
MEKK2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MAP3K2,
Species
human
MISSION® esiRNA, targeting mouse Map3k2,
Species
mouse