MilliporeSigma

MAPK7

mitogen-activated protein kinase 7

Synonyms:
BMK1, ERK4, ERK5, PRKM7
Species:
UniProtKB ID:
Gene ID:
  • Human(5598) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(23939) mitogen-activated protein kinase 7
  • Rat(114509) mitogen-activated protein kinase 7
  • Zebrafish(541323) mitogen-activated protein kinase 7
  • domestic cat(101097357) mitogen-activated protein kinase 7
  • cow(537703) mitogen-activated protein kinase 7
  • dog(489532) mitogen-activated protein kinase 7
  • Domestic Rabbit(100338535) mitogen-activated protein kinase 7
  • sheep(101110073) mitogen-activated protein kinase 7
  • naked mole-rat(101726391) mitogen-activated protein kinase 7
  • domestic guinea pig(100728396) mitogen-activated protein kinase 7

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MAPK7, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-MAPK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ERK5 Antibody, clone 5C1P5, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-phospho-ERK5 (pThr218/pTyr220) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
Anti-ERK5 Antibody, clone 2H15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, porcine
Application
ELISA
affinity binding assay

immunofluorescence

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
ERK5, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MAPK7,
Species
human
MISSION® esiRNA, targeting mouse Mapk7,
Species
mouse