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MMP13

matrix metallopeptidase 13 (collagenase 3)

Synonyms:
CLG3, MANDP1
Species:
UniProtKB ID:
Gene ID:
  • Human(4322) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17386) matrix metallopeptidase 13
  • Rat(171052) matrix metallopeptidase 13
  • naked mole-rat(101699013) matrix metallopeptidase 13 (collagenase 3)
  • sheep(443113) matrix metallopeptidase 13 (collagenase 3)
  • cow(281914) matrix metallopeptidase 13 (collagenase 3)
  • Domestic Rabbit(100008685) matrix metallopeptidase 13 (collagenase 3)
  • domestic guinea pig(100731756) matrix metallopeptidase 13 (collagenase 3)
  • chicken(395683) matrix metallopeptidase 13 (collagenase 3)
  • domestic cat(493679) matrix metallopeptidase 13 (collagenase 3)
  • dog(403763) matrix metallopeptidase 13 (collagenase 3)
  • Horse(100009711) matrix metallopeptidase 13 (collagenase 3)

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ELISA

Product Number
Description
Species
Human MMP-13 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MMP13 antibody produced in mouse, clone 3B11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)

western blot
Anti-MMP-13 Antibody, clone VIIIA2, clone VIIIA2, Chemicon®, from mouse,
Species Reactivity
human, mouse, rabbit
Application
immunohistochemistry
Anti-MMP13 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-MMP13 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
guinea pig, horse, human, rabbit, rat
Application
western blot
Anti-MMP-13 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Doxycycline Monohydrate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Doxycycline monohydrate, ,
Species
human
Marimastat, ≥98% (HPLC),
Species
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Species
human, rat, mouse
CP-471474, ≥98% (HPLC),
Species
human, rat, mouse

Proteins

Product Number
Description
Species
MMP-13, human, proform, his-tagged, E. coli recombinant, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MMP13,
Species
human