MTA1
metastasis associated 1
Synonyms:
Species:
Human MTA1 (9112), Mouse Mta1 (116870), Rat Mta1 (64520), domestic guinea pig Mta1 (100731798), naked mole-rat Mta1 (101721757), chicken MTA1 (429060), domestic cat MTA1 (101090194), Horse MTA1 (100146742), dog MTA1 (480450), cow MTA1 (511438)
UniProtKB ID:
Gene ID:
- Human(9112) Summary: This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
- Mouse(116870) metastasis associated 1
- Rat(64520) metastasis associated 1
- domestic guinea pig(100731798) metastasis associated 1
- naked mole-rat(101721757) metastasis associated 1
- chicken(429060) metastasis associated 1
- domestic cat(101090194) metastasis associated 1
- Horse(100146742) metastasis associated 1
- dog(480450) metastasis associated 1
- cow(511438) metastasis associated 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MTA1 antibody produced in mouse, clone 4D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
mouse
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-MTA1 antibody produced in mouse, clone 4D5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MTA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-MTA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-MTA1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunoprecipitation (IP)
microarray
western blot
microarray
western blot