MilliporeSigma

MUC1

mucin 1, cell surface associated

Synonyms:
CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM
Species:
UniProtKB ID:
Gene ID:
  • Human(4582) Summary: This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
  • Mouse(17829) mucin 1, transmembrane
  • Rat(24571) mucin 1, cell surface associated
  • dog(448784) mucin 1, cell surface associated
  • naked mole-rat(101702421) mucin 1, cell surface associated
  • domestic cat(101093832) mucin 1, cell surface associated
  • chicken(426412) mucin 1, cell surface associated
  • domestic cat(100294522) mucin 1, cell surface associated
  • cow(281333) mucin 1, cell surface associated
  • domestic guinea pig(100733534) mucin 1, cell surface associated
  • sheep(100294589) mucin 1, cell surface associated
  • sheep(101106133) mucin 1, cell surface associated
  • Domestic Rabbit(100009240) mucin 1, cell surface associated

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ELISA

Product Number
Description
Species
Human Carbohydrate Antigen 15-3 / Mucin-1 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
MUC1 (MRQ-17) Mouse Monoclonal Antibody, ,
Species Reactivity
human
Application
immunohistochemistry
Anti-MUC1 Antibody, clone HMFG2, clone HMFG2, from mouse,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-MUC1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL8733, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-MUC1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, human
Application
immunohistochemistry
western blot
Anti-MUC1 antibody , Mouse monoclonal, clone 1D1, purified from hybridoma cell culture,
Species Reactivity
human
Application
ELISA
immunocytochemistry

immunoprecipitation (IP)

radioimmunoassay

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MUC1,
Species
human