PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
Synonyms:
C2-PI3K
Species:
Human PIK3C2B (5287), Mouse Pik3c2b (240752), Rat Pik3c2b (289021), Domestic Rabbit PIK3C2B (100351938), dog PIK3C2B (478938), Zebrafish pik3c2b (567938), chicken PIK3C2B (419822), sheep PIK3C2B (101108766), cow PIK3C2B (537396), Horse PIK3C2B (100054391) ...More
UniProtKB ID:
Gene ID:
- Human(5287) Summary: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008]
- Mouse(240752) phosphoinositide-3-kinase, class 2, beta polypeptide
- Rat(289021) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
- Domestic Rabbit(100351938) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
- dog(478938) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
- Zebrafish(567938) phosphoinositide-3-kinase, class 2, beta polypeptide
- chicken(419822) phosphoinositide-3-kinase, class 2, beta polypeptide
- sheep(101108766) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
- cow(537396) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
- Horse(100054391) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
- domestic cat(101082204) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
- naked mole-rat(101721434) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
- domestic guinea pig(100719801) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PIK3C2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-PIK3C2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
esiRNA
Product Number
Description
Species