MilliporeSigma

PPM1B

protein phosphatase, Mg2+/Mn2+ dependent, 1B

Synonyms:
PP2C-beta-X, PP2CB, PP2CBETA, PPC2BETAX
Species:
UniProtKB ID:
Gene ID:
  • Human(5495) Summary: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008]
  • Mouse(19043) protein phosphatase 1B, magnesium dependent, beta isoform
  • Rat(24667) protein phosphatase, Mg2+/Mn2+ dependent, 1B
  • Domestic Rabbit(100356616) protein phosphatase, Mg2+/Mn2+ dependent, 1B
  • sheep(101112467) protein phosphatase, Mg2+/Mn2+ dependent, 1B
  • cow(281995) protein phosphatase, Mg2+/Mn2+ dependent, 1B
  • Horse(100053585) protein phosphatase, Mg2+/Mn2+ dependent, 1B
  • naked mole-rat(101724963) protein phosphatase, Mg2+/Mn2+ dependent, 1B
  • domestic guinea pig(100719242) protein phosphatase, Mg2+/Mn2+ dependent, 1B
  • domestic cat(101094170) protein phosphatase, Mg2+/Mn2+ dependent, 1B
  • dog(474573) protein phosphatase, Mg2+/Mn2+ dependent, 1B
  • chicken(421404) protein phosphatase, Mg2+/Mn2+ dependent, 1B

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PPM1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PPM1B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PPM1B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
Monoclonal Anti-PPM1B antibody produced in mouse, clone 1A3-2A4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunoprecipitation (IP)

proximity ligation assay

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PPM1B,
Species
human
MISSION® esiRNA, targeting mouse Ppm1b,
Species
mouse