MilliporeSigma

PRAME

preferentially expressed antigen in melanoma

Synonyms:
CT130, MAPE, OIP-4, OIP4
Species:
UniProtKB ID:
Gene ID:
  • Human(23532) Summary: This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(75829) preferentially expressed antigen in melanoma
  • Rat(680000) preferentially expressed antigen in melanoma
  • naked mole-rat(101711995) preferentially expressed antigen in melanoma
  • dog(477552) preferentially expressed antigen in melanoma
  • Horse(100061889) preferentially expressed antigen in melanoma
  • domestic cat(101086260) preferentially expressed antigen in melanoma
  • cow(528601) preferentially expressed antigen in melanoma
  • cow(785023) preferentially expressed antigen in melanoma
  • sheep(101108258) preferentially expressed antigen in melanoma
  • domestic guinea pig(100731688) preferentially expressed antigen in melanoma

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PRAME antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
ANTI-MAPE(C-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry

western blot
Anti-PRAME antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Prame,
Species
mouse
MISSION® esiRNA, targeting human PRAME,
Species
human