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PTK6

protein tyrosine kinase 6

Synonyms:
BRK
Species:
UniProtKB ID:
Gene ID:
  • Human(5753) Summary: The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
  • Mouse(20459) PTK6 protein tyrosine kinase 6
  • Rat(366275) protein tyrosine kinase 6
  • cow(529814) PTK6 protein tyrosine kinase 6
  • Horse(100060532) PTK6 protein tyrosine kinase 6
  • domestic cat(101100294) PTK6 protein tyrosine kinase 6
  • naked mole-rat(101722381) protein tyrosine kinase 6
  • domestic guinea pig(100731622) protein tyrosine kinase 6
  • sheep(101109378) PTK6 protein tyrosine kinase 6

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PTK6, (C-terminal) antibody produced in mouse, clone 2F11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
Anti-Brk Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-phospho-Brk (Tyr342) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-PTK6 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-PTK6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Proteins

Product Number
Description
Species
BRK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
Brk Protein, active, 10 µg, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PTK6,
Species
human
MISSION® esiRNA, targeting mouse Ptk6,
Species
mouse