MilliporeSigma

QARS

glutaminyl-tRNA synthetase

Synonyms:
GLNRS, PRO2195
Species:
UniProtKB ID:
Gene ID:
  • Human(5859) Summary: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
  • Mouse(97541) glutaminyl-tRNA synthetase
  • Rat(290868) glutaminyl-tRNA synthetase
  • naked mole-rat(101702219) glutaminyl-tRNA synthetase
  • cow(514586) glutaminyl-tRNA synthetase
  • sheep(101106974) glutaminyl-tRNA synthetase
  • Zebrafish(394188) glutaminyl-tRNA synthetase
  • chicken(416057) glutaminyl-tRNA synthetase
  • dog(476628) glutaminyl-tRNA synthetase
  • domestic cat(101081368) glutaminyl-tRNA synthetase
  • domestic guinea pig(100731498) glutaminyl-tRNA synthetase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-QARS antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-QARS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-QARS antibody produced in mouse, clone 5F5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-QARS antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
Anti-QARS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Qars,
Species
mouse
MISSION® esiRNA, targeting human QARS,
Species
human