RANBP2
RAN binding protein 2
Synonyms:
ANE1, IIAE3, NUP358, TRP1, TRP2
Species:
Human RANBP2 (5903), Mouse Ranbp2 (19386), Rat Ranbp2 (294429), Horse RANBP2 (100060826), dog RANBP2 (474539), cow RANBP2 (785768), domestic cat RANBP2 (101094012), chicken RANBP2 (418730), domestic guinea pig Ranbp2 (101788077), sheep RANBP2 (101116816)
UniProtKB ID:
Gene ID:
- Human(5903) Summary: RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. [provided by RefSeq, Jul 2008]
- Mouse(19386) RAN binding protein 2
- Rat(294429) RAN binding protein 2
- Horse(100060826) RAN binding protein 2
- dog(474539) RAN binding protein 2
- cow(785768) RAN binding protein 2
- domestic cat(101094012) RAN binding protein 2
- chicken(418730) RAN binding protein 2
- domestic guinea pig(101788077) RAN binding protein 2
- sheep(101116816) RAN binding protein 2
- naked mole-rat(101698338) RAN binding protein 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RANBP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-RANBP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-RANBP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-RANBP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence