MilliporeSigma

RARB

retinoic acid receptor, beta

Synonyms:
HAP, NR1B2, RRB2
Species:
UniProtKB ID:
Gene ID:
  • Human(5915) Summary: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(218772) retinoic acid receptor, beta
  • Rat(24706) retinoic acid receptor, beta
  • Domestic Rabbit(100358445) retinoic acid receptor, beta
  • sheep(101122663) retinoic acid receptor, beta
  • cow(616895) retinoic acid receptor, beta
  • Horse(100051546) retinoic acid receptor, beta
  • domestic cat(101085742) retinoic acid receptor, beta
  • dog(477045) retinoic acid receptor, beta
  • domestic guinea pig(100379264) retinoic acid receptor, beta
  • chicken(396266) retinoic acid receptor, beta
  • naked mole-rat(101724485) retinoic acid receptor, beta

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Small Molecule - Activator

Product Number
Description
Species
9-cis-Retinoic acid, ≥98% (HPLC),
Species
human
Retinoic acid, ≥98% (HPLC), powder,
Species
mouse, human

Small Molecule - Agonist

Product Number
Description
Species
AM580, ≥98% (HPLC),
Species
human
Isotretinoin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Tretinoin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Tretinoin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Isotretinoin, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
AM580, ≥98% (HPLC),
Species
human
CD437, ≥98% (HPLC), solid,
Species
human
TTNPB, ,
Species
human
Retinoic acid, ≥98% (HPLC), powder,
Species
mouse, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RARβ Antibody, clone 6D5V4, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
immunofluorescence
western blot
Anti-RARB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
Anti-Retinoic Acid Receptor β, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot

Small Molecule - Ligand

Product Number
Description
Species
TTNPB, ,
Species
human
9-cis-Retinoic acid, ≥98% (HPLC),
Species
human
Retinoic acid, ≥98% (HPLC), powder,
Species
mouse, human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
Retinoic acid, ≥98% (HPLC), powder,
Species
mouse, human

Proteins

Product Number
Description
Species
RARβ, ligand binding domain (173-409), GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
RAR, β human, recombinant, expressed in E. coli, ≥75% (SDS-PAGE),
Species
human
RAR β-ligand binding domain (173-409) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Rarb,
Species
mouse
MISSION® esiRNA, targeting human RARB,
Species
human