Skip to Content
MilliporeSigma

RGS10

regulator of G-protein signaling 10

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(6001) Summary: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(67865) regulator of G-protein signalling 10
  • Rat(54290) regulator of G-protein signaling 10
  • naked mole-rat(101718163) regulator of G-protein signaling 10
  • chicken(423930) regulator of G-protein signaling 10
  • domestic cat(101089300) regulator of G-protein signaling 10
  • cow(614550) regulator of G-protein signaling 10
  • sheep(101107650) regulator of G-protein signaling 10
  • domestic guinea pig(100716128) regulator of G-protein signaling 10
  • dog(477840) regulator of G-protein signaling 10

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RGS10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-RGS10 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-RGS10 antibody produced in mouse, clone 1G9-2D4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-RGS10, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
flow cytometry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RGS10,
Species
human
MISSION® esiRNA, targeting mouse Rgs10,
Species
mouse