MilliporeSigma

RUNX1

runt-related transcription factor 1

Synonyms:
AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2aB
Species:
UniProtKB ID:
Gene ID:
  • Human(861) Summary: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12394) runt related transcription factor 1
  • Rat(50662) runt-related transcription factor 1
  • chicken(396152) runt-related transcription factor 1
  • Zebrafish(58126) runt-related transcription factor 1
  • sheep(101108280) runt-related transcription factor 1
  • Domestic Rabbit(100358993) runt-related transcription factor 1
  • domestic guinea pig(100724149) runt-related transcription factor 1
  • domestic cat(101084898) runt-related transcription factor 1
  • cow(529631) runt-related transcription factor 1
  • dog(487746) runt-related transcription factor 1
  • naked mole-rat(101705852) runt-related transcription factor 1

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-RUNX1 antibody produced in mouse, clone 2C10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-AML1 (pSer435) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-phospho-AML1 (pSer276) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-phospho-AML1 (pSer303) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-AML1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RUNX1,
Species
human
MISSION® esiRNA, targeting mouse Runx1,
Species
mouse