SDC1
syndecan 1
CD138, SDC, SYND1, syndecan
Human SDC1 (6382), Mouse Sdc1 (20969), Rat Sdc1 (25216), sheep SDC1 (101106837), domestic cat SDC1 (101101459), chicken SDC1 (421960), cow SDC1 (529759), naked mole-rat Sdc1 (101723528), dog SDC1 (482986)
- Human(6382) Summary: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]
- Mouse(20969) syndecan 1
- Rat(25216) syndecan 1
- sheep(101106837) syndecan 1
- domestic cat(101101459) syndecan 1
- chicken(421960) syndecan 1
- cow(529759) syndecan 1
- naked mole-rat(101723528) syndecan 1
- dog(482986) syndecan 1
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