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SIGLEC1

sialic acid binding Ig-like lectin 1, sialoadhesin

Synonyms:
CD169, SIGLEC-1, SN, dJ1009E24.1
Species:
UniProtKB ID:
Gene ID:
  • Human(6614) Summary: This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(20612) sialic acid binding Ig-like lectin 1, sialoadhesin
  • Rat(311426) sialic acid binding Ig-like lectin 1, sialoadhesin
  • dog(485794) sialic acid binding Ig-like lectin 1, sialoadhesin
  • domestic cat(101093264) sialic acid binding Ig-like lectin 1, sialoadhesin
  • Horse(100066351) sialic acid binding Ig-like lectin 1, sialoadhesin
  • Domestic Rabbit(100345836) sialic acid binding Ig-like lectin 1, sialoadhesin
  • domestic guinea pig(100713768) sialic acid binding Ig-like lectin 1, sialoadhesin
  • sheep(101110959) sialic acid binding Ig-like lectin 1, sialoadhesin
  • cow(539759) sialic acid binding Ig-like lectin 1, sialoadhesin
  • naked mole-rat(101698560) sialic acid binding Ig-like lectin 1, sialoadhesin

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ELISA

Product Number
Description
Species
Human Siglec-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SIGLEC1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Siglec1/CD169 Antibody, clone 1O8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunohistochemistry

western blot
Anti-Siglec-1 (CD169) Antibody, clone 5F1.1, clone 5F1.1, from mouse,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-CD169 antibody, Rabbit monoclonal, clone SP213, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-CD169 antibody, Rabbit monoclonal, clone SP216, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Siglec1,
Species
mouse
MISSION® esiRNA, targeting human SIGLEC1,
Species
human