SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Synonyms:
BAF190, BAF190A, BRG1, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b
Species:
Human SMARCA4 (6597), Mouse Smarca4 (20586), Rat Smarca4 (171379), dog SMARCA4 (476710), sheep SMARCA4 (101116565), domestic cat SMARCA4 (101097046), Zebrafish smarca4 (353295), chicken SMARCA4 (395932), cow SMARCA4 (414274), naked mole-rat Smarca4 (101700987)
UniProtKB ID:
Gene ID:
- Human(6597) Summary: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
- Mouse(20586) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- Rat(171379) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- dog(476710) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- sheep(101116565) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- domestic cat(101097046) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- Zebrafish(353295) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- chicken(395932) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- cow(414274) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- naked mole-rat(101700987) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- domestic guinea pig(100719729) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Smarca4 Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL13783, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-Smarca4 Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL13779, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-SMARCA4 antibody produced in rabbit, ,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SNF2β/BRG1 Antibody, serum, Upstate®,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-SMARCA4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Proteins
esiRNA
Product Number
Description
Species