TIMP1
TIMP metallopeptidase inhibitor 1
Synonyms:
CLGI, EPA, EPO, HCI, TIMP
Species:
Human TIMP1 (7076), Mouse Timp1 (21857), Rat Timp1 (116510), domestic cat TIMP1 (101095886), naked mole-rat Timp1 (101722238), dog TIMP1 (403816), cow TIMP1 (282092), domestic guinea pig Timp1 (101787552), sheep TIMP1 (443331), Horse TIMP1 (100034220)
UniProtKB ID:
Gene ID:
- Human(7076) Summary: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]
- Mouse(21857) tissue inhibitor of metalloproteinase 1
- Rat(116510) TIMP metallopeptidase inhibitor 1
- domestic cat(101095886) TIMP metallopeptidase inhibitor 1
- naked mole-rat(101722238) TIMP metallopeptidase inhibitor 1
- dog(403816) TIMP metallopeptidase inhibitor 1
- cow(282092) TIMP metallopeptidase inhibitor 1
- domestic guinea pig(101787552) TIMP metallopeptidase inhibitor 1
- sheep(443331) TIMP metallopeptidase inhibitor 1
- Horse(100034220) TIMP metallopeptidase inhibitor 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TIMP1 antibody produced in mouse, clone 4D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-TIMP1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, sheep
Application
western blot
Anti-TIMP-1 Antibody, clone 1H19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TIMP-1 (Ab-1) Mouse mAb (7-6C1), liquid, clone 7-6C1, Calbiochem®,
Species Reactivity
bovine, human, rat
Application
Anti-TIMP-1 Antibody, clone 147-6D11, clone 147-6D11, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
TIMP-1 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human