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UNC13B

unc-13 homolog B (C. elegans)

Synonyms:
MUNC13, UNC13, Unc13h2
Species:
UniProtKB ID:
Gene ID:
  • Human(10497) Summary: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]
  • Mouse(22249) unc-13 homolog B (C. elegans)
  • Rat(64830) unc-13 homolog B (C. elegans)
  • Horse(100055666) unc-13 homolog B (C. elegans)
  • domestic guinea pig(100726943) unc-13 homolog B (C. elegans)
  • naked mole-rat(101717680) unc-13 homolog B (C. elegans)
  • cow(530692) unc-13 homolog B (C. elegans)
  • sheep(101117731) unc-13 homolog B (C. elegans)
  • Domestic Rabbit(100345810) unc-13 homolog B (C. elegans)
  • domestic cat(101089655) unc-13 homolog B (C. elegans)
  • dog(100683511) unc-13 homolog B (C. elegans)

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-UNC13B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-UNC13B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human UNC13B,
Species
human