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USP15

ubiquitin specific peptidase 15

Synonyms:
UNPH-2, UNPH4
Species:
UniProtKB ID:
Gene ID:
  • Human(9958) Summary: This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011]
  • Mouse(14479) ubiquitin specific peptidase 15
  • Rat(171329) ubiquitin specific peptidase 15
  • chicken(395644) ubiquitin specific peptidase 15
  • Horse(100055857) ubiquitin specific peptidase 15
  • sheep(101113139) ubiquitin specific peptidase 15
  • domestic cat(101099566) ubiquitin specific peptidase 15
  • dog(474424) ubiquitin specific peptidase 15
  • naked mole-rat(101719900) ubiquitin specific peptidase 15
  • domestic guinea pig(100734747) ubiquitin specific peptidase 15
  • cow(538284) ubiquitin specific peptidase 15
  • Domestic Rabbit(100356438) ubiquitin specific peptidase 15
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