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T6769

Sigma-Aldrich

Lipopolysaccharides from Escherichia coli O128:B12

trinitrophenyl conjugate

Synonym(s):

LPS

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About This Item

CAS Number:
93572-42-0
EC Number:
297-473-0
MDL number:
MFCD00164401
UNSPSC Code:
12352211
Pricing and availability is not currently available.

biological source

Escherichia coli (O128:B12)

conjugate

trinitrophenyl conjugate

assay

≥98% (TLC)

form

powder

extent of labeling

15-60 μg trinitrophenolmg LPS

shipped in

ambient

storage temp.

2-8°C

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Application

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
12160601

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Jun Liu et al.
World journal of gastroenterology, 15(16), 2009-2015 (2009-04-29)
To investigate the effect of Lianshu preparation on lipopolysaccharide (LPS)-induced diarrhea in rats. A diarrhea model was established in Sprague Dawley rats via injection of 1 mL of 30 mg/kg LPS. A total of 40 rats were randomly divided into
Kea Martin et al.
Journal of immunology (Baltimore, Md. : 1950), 203(11), 2791-2806 (2019-10-30)
The paracaspase Malt1 is a key regulator of canonical NF-κB activation downstream of multiple receptors in both immune and nonimmune cells. Genetic disruption of Malt1 protease function in mice and MALT1 mutations in humans results in reduced regulatory T cells

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