Skip to Content
MilliporeSigma

Ocriplasmin for vitreoretinal diseases.

Journal of biomedicine & biotechnology (2012-11-30)
Irena Tsui, Carolyn K Pan, Ehsan Rahimy, Steven D Schwartz
ABSTRACT

Fibronectin and laminin are clinically relevant plasmin receptors in the eye. Located at the vitreoretinal interface, they are cleaved by ocriplasmin (Microplasmin, ThromboGenics, Iselin, NJ), a novel ophthalmic medication. A series of clinical trials to study ocriplasmin for the treatment of vitreoretinal diseases such as vitreomacular traction, macular hole, and exudative age-related macular degeneration are underway. The results are promising and may impact patient care.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Plasmin from human plasma, lyophilized powder, ≥2.0 units/mg protein