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  • Tri- and hexavalent mannoside clusters as potential inhibitors of type 1 fimbriated bacteria using pentaerythritol and triazole linkages.

Tri- and hexavalent mannoside clusters as potential inhibitors of type 1 fimbriated bacteria using pentaerythritol and triazole linkages.

Chemical communications (Cambridge, England) (2007-01-16)
Mohamed Touaibia, Tze Chieh Shiao, Alex Papadopoulos, Jonathan Vaucher, Qingan Wang, Karima Benhamioud, René Roy
ABSTRACT

Several oligomannoside clusters having a hundred-fold increase in affinities toward E. coli were synthesized by Cu(I)-catalyzed [1,3]-dipolar cycloadditions using pentaerythritol scaffolds bearing either alkyne or azide functionalities.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Pentaerythritol, 99%
Sigma-Aldrich
Pentaerythritol, 98%