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Contact depigmentation induced by propyl gallate.

Clinical and experimental dermatology (2011-05-14)
D Pandhi, A Vij, A Singal
ABSTRACT

We report a 41-year-old woman who developed contact depigmentation at several body sites after using lipstick, liquid kumkum (a colouring usually made from turmeric or saffron used for social/religious markings), and plastic or rubber slippers (flip-flops). Propyl gallate, a common ingredient to all and a previously undocumented depigmenting agent, was incriminated on patch testing with the Indian standard series.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Propyl gallate, for microscopy, ≥98.0% (HPLC)
Sigma-Aldrich
Propyl gallate, antioxidant, ≥98.0% (HPLC)
Sigma-Aldrich
Propyl gallate, ≥98%, FCC
Sigma-Aldrich
Propyl gallate, powder
Supelco
Propyl gallate, Pharmaceutical Secondary Standard; Certified Reference Material