- DBU-catalyzed tandem additions of electron-deficient 1,3-conjugated enynes with 2-aminomalonates: a facile access to highly substituted 2-pyrrolines.
DBU-catalyzed tandem additions of electron-deficient 1,3-conjugated enynes with 2-aminomalonates: a facile access to highly substituted 2-pyrrolines.
Chemical communications (Cambridge, England) (2012-03-17)
Xiuzhao Yu, Guanghua Zhou, Junliang Zhang
PMID22422110
ABSTRACT
An efficient, metal free approach to highly substituted 2-pyrrolines by DBU-catalyzed tandem additions (a formal [3+2] cycloaddition) of electron-deficient 1,3-conjugated enynes and 2-aminomalonates under mild conditions was developed.