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  • Pd(II)-catalyzed synthesis of benzisoxazolones from benzohydroxamic acids via C-H activation.

Pd(II)-catalyzed synthesis of benzisoxazolones from benzohydroxamic acids via C-H activation.

The Journal of organic chemistry (2012-08-18)
Xi-Ai Gao, Ru-Long Yan, Xian-Xue Wang, Hao Yan, Jian Li, Han Guo, Guo-Sheng Huang
ABSTRACT

A Pd-catalyzed method for the synthesis of benzisoxazolones from benzohydroxamic acids using Oxone as an oxidant in a one-pot procedure has been developed. In this process, the reaction appears to be suitable for construction of various benzisoxazolones.

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Sigma-Aldrich
Benzhydroxamic acid, 99%